Search on: 2,3-DIPHOSPHOGLYCERIC ACID 
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Descriptor English:   2,3-Diphosphoglycerate 
Descriptor Spanish:   2,3-Difosfoglicerato 
Descriptor Portuguese:   2,3-Difosfoglicerato 
Synonyms English:   2,3-Bisphosphoglycerate
2,3-Diphosphoglyceric Acid
2,3-DPG  
Tree Number:   D02.241.081.844.387.388.175
D02.241.511.902.387.388.175
D02.705.196.175
D09.811.366.388.175
Definition English:   A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508) 
Entry Combination - descr/qualif English:   2,3-Diphosphoglycerate/analogs & derivatives use Diphosphoglyceric Acids
 
History Note English:   98; use 2,3-DIPHOSPHOGLYCERATE (NM) 1980-97 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   33399 
Unique Identifier:   D019794 

Occurrence in VHL:
 

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